Inertial confinement fusion (ICF) implosions require very high levels of symmetry in order to reach the high densities and temperatures required for fusion induced self-heating. Even percent-level deviations from perfect spherical symmetry can lead to significant distortions of the implosion and ultimately degrade fusion performance.
source https://phys.org/news/2021-02-reveals-d-asymmetry-inertial-confinement.html