Monday 15 April 2019

New algorithm identifies patients harboring tumor-causing defect found in multiple cancers

Medications known as PARP inhibitors have emerged as a promising therapy for several forms of cancer fueled by a defect in the cells' DNA repair machinery. Yet many people with cancers caused by the defect, known as HR deficiency, who stand to benefit from PARP inhibitors remain unidentified because standard genetic panels used in the clinic do not reliably detect the cancer-causing HR deficiency.

* This article was originally published here